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The hematological and urinary parameters can serve as indicators of susceptibilities of pregnant women to infectious diseases. Early detection of such fatal infections like Human Immunodeficiency Virus (HIV) can go a long way in mitigating perinatal mortality. This study evaluates the frequency of occurrence of HIV in pregnant women with a set of hematological and urinary parameters. Four hundred (400) pregnant women in Ikere-Ekiti in Ekiti-state, stratified in age groups were recruited in the study. Blood and urine samples were examined for blood group, packed cell volume (PCV), HIV status and some urine parameters. In the results, the age range (25-29) had the highest number (144) among the pregnant women while age range ≥35 had the least. Women in blood group O had the highest number (54%), this is followed by group B (21.5%) and group A while group AB (4.5%) had the least. The prevalence of HIV among the different blood groups (A, B, AB and O) was respectively 0.5%, 1.5%, 2.0% and 0.3%, the overall prevalence of HIV was 17(4.3%) and the highest occurred in the age group ≥35. Women of rhesus positive had the highest prevalence of HIV (4.0%). The 3.0% of 49% who were anemic had HIV infection. The incidence of positivity to some urine parameters among the pregnant women who were positive to HIV were glucose (0.3%), protein (0.5%), ketone and nitrite 0%. From these results, there might be a relationship between some hematological and urinary parameters with HIV status among the pregnant women, further studies will involve carrying out metabolomics study to ascertain the real relationship.
Osonuga IO, Osonuga OA, Onadeko AA, Osonuga A, Osonuga AA. Hematological profile of pregnant women in southwest of Nigeria. Asian Pacific Journal of Tropical Disease. 2011;1(3):232–234.
Anoubissi JD, Gabriel EL, Kengne Nde C, Fokam J, Tseuko DG, Messeh A. Factors associated with risk of HIV-infection in pregnant women in Cameroon: Evidence from the 2016 national sentinel surveillance survey of HIV and syphilis. Plos One. 2019;14(4):1-10.
Grace S, Melina TH, Hastina J, Baill S. Anaemia in pregnancy, prevalence, risk factors and adverse prenatal outcomes in northern Tangama; 2018.
Agata SK, Bartlomie M, Agnieszka B, Marcin P, Ewafirlag BH, Justinah DK. Factors associated with urinary tract infections among HIV-1 infected patients. Plos one Journal. 2018;13(1):e0195664.
Jacquelyn C. Why are there nitrites in my urine?; 2017.
Airoldi J, Weinstein L. Clinical Significance of proteinuria in pregnancy. Obstet Gynecol Surv. 2007;62(2):117-124.
Simerville JA, Maxted WC, Pahira JJ. Urinalysis: A comprehensive review. American Family Physician. 2005;71(6): 1153–1162.
Helen LR, Helen LB, Katie F, Leome KC, Martoe DN. Prevalence of maternal urinary ketones in pregnancy in overweight and obese women. Journal of Obstetric Medicine. 2018;11(2):79-82.
Chris I. Ketone in gestational diabetes; 2009.
CDC (Centre for Disease Control and Prevention). HIV: Transmission, symptoms and treatment; 2018.
WHO (World Health Organization). Consolidated guidelines on the use of antiretroviral drugs for treating and preventing HIV infection. Recommen-dations for a public health approach. Second Edition; 2016.
Pope M, Haase AT. Transmission, acute HIV-1 infection and the quest for strategies to prevent infection. Nature Medicine. 2003;9(7):84752.
ACOG (American College of Obstetricians and Gynaecologists); 2018.
Jane Kirby Press Association. Type O blood may have fertility barrier; 2010.
Carine NN, Celine NN, Babara AT, Dara M. ABO- rhesus blood groups and susceptibility to HIV infection. Journal of Pharmaceutical and Biological Sciences. 2015;3:324-328.
Abdulazeez AA, Alo EB, Rebecca SN. Carriage rate of Human Immunodeficiency Virus (HIV) infection among different ABO and Rhesus blood groups in Adamawa state, Nigeria. Biomedical Research. 2008; 19(1):41-44.
Laura C. Blood groups in infections and host susceptibility. Clinical Microbiology Review. 2015;28(3):801-810.
Glenn ER. What does your blood type mean for your health; 2015.
Obinkorang C, Yeboah FA. Blood haemoglobin measurement as a predictive indicator for the progression of HIV/AIDS in resource- limited setting. Journal of Biomedical Science. 2009;6(1):102.
Shomon M. Gestational diabetes, retrieved from Health Central (live bold); 2019.
Micheal C. Levels of albumin in Urine higher in people wiht HIV association with risk of heart and kidney disease; 2007.