Inheritance of ABO Blood Group and Rhesus Factor and It Implication in Genetic Counselling and Public Health Education

Albert Opoku *

Nursing and Midwifery Training College, Tepa, Ghana and Trinity Hospital Pankrono, Kumasi, Ghana.

Kofi Baffoe-Sarpong

Nursing and Midwifery Training College, Asankragwa, Ghana.

Agyemang Prempeh Charles

Nursing and Midwifery Training College, Dormaa, Ghana.

Abdul Karim Boakye Yiadom

Nursing and Midwifery Training College, Sekondi Ghana.

Boateng Acheampong Emmanuel

Nursing and Midwifery Training College, Dunkwa on Offin Ghana.

*Author to whom correspondence should be addressed.


Abstract

Introduction: The discovery of the ABO Blood Group and rhesus factor, over century ago, triggered countless enthusiasm. Before then, all blood had been presumed to be the matching, and the often tragic consequences of blood transfusions were not understood.

Objective: The objective of this article sought to explain Inheritance of ABO Blood Group and Rhesus factor which would contribute to knowledge and help in Genetic Counselling.

Methodology: This is a scoping review to explain Inheritance of ABO Blood Group and Rhesus factor. The LILACS-BIREME, SCIELO, PUBMED, ACADEMIA, SCIENCE DOMAIN databases, some textbooks and google scholar were accessed for the study. Scientific papers published in English were reviewed.  A total of 35 reports published were identified and reviewed. Twenty five (25) publications meeting the inclusion criterion were selected for this review. Finally, an analysis was conducted and the papers were assessed in agreement with the study objectives. 

Findings: Determining an individual’s blood group is important prior to blood transfusion and prior to the donation or receiving of a kidney transplant. Although blood group studies cannot be used to prove paternity, they can provide unequivocal evidence that a male is not the father of a particular child. Aside knowing your genotype before marriage, there is the need for one to know about Rhesus factor to prevent Rhesus factor incompatibility.

Conclusion: The discussion and knowledge generated on the ABO blood group and the Rhesus factor could be used in genetic counselling and public health education to prevent transfusion reaction and Rhesus factor incompatibility.

Keywords: Inheritance, ABO blood group, rhesus factor, genetic counselling


How to Cite

Opoku , A., Baffoe-Sarpong , K., Charles , A. P., Yiadom , A. K. B., & Emmanuel , B. A. (2024). Inheritance of ABO Blood Group and Rhesus Factor and It Implication in Genetic Counselling and Public Health Education. International Journal of Research and Reports in Hematology, 7(1), 5–12. Retrieved from https://journalijr2h.com/index.php/IJR2H/article/view/136

Downloads

Download data is not yet available.

References

Hilde E. Groot Laura E. Villegas Sierra, M Abdullah Said, Erik Lipsic, Jacco C. Karper and pim van der harst. Genetically determined ABO blood group and its associations with health and disease, arteriosclerosis, thrombosis, and vascular Biology. 2020;40:830–838.

Reid ME, Lomas-Francis C. The blood group antigen facts book. second ed. New York: Elsevier Academic Press; 2004.

Maton Anthea, Jean Hopkins, Charles William McLaughlin, Susan Johnson, Maryanna Quon Warner, David LaHart, Jill D. Wright human biology and health. Englewood Cliffs, New Jersey, USA: Prentice Hall; 1993.

Schreiber BA; Curley R; Gaur A; Rodriguez E; Rogers K; Sinha S. "ABO blood group system". Encyclopædia Britannica. Encyclopædia Britannica, Inc; 2017, 18 July. Retrieved 26 October 2017.

Scanlon VC, Sanders T. Essentials of Anatomy and Physiology (12th Ed) USA, F. A. Davis company. 2018;9.

Adams J. Paternity testing: Blood types and DNA. Nature Education. 2008;1(1): 146.

Daniels G. Human blood groups, Second ed. Blackwell Science; 2002.

Hilde EG, Laura EVS, M Abdullah S, Erik L, Jacco CK, Pim van der H. Genetically determined ABO blood group and its associations with health and disease, arteriosclerosis, thrombosis, and vascular biology. 2020;40:830–838.

Reid ME, Lomas-Francis C. The blood group antigen facts book. Second ed. 2004, New York: Elsevier Academic Press; 2004.

"Red cell immunogenetics and blood group terminology“. International Society of Blood Transfusion. Archived from the original on 8 July 2020. Retrieved 4 October 2020; 2019.

Curley R. Erythroblastosis Fetalis Pathology. Retrieved, 4th May 4, 2022. Available:https://www.britannica.com/science/erythroblastosis-fetalis

Lori smith what is erythroblastosis fetalis? Medical news today, September 28; 2018. Available: https://www.medicalnewstoday.com/articles/314472 retrieved, 4th May 4, 2022.

Reid ME, Lomas-Francis C. The blood group antigen facts book. Second ed. New York: Elsevier Academic Press; 2004.

Dean L. Blood groups and red cell antigens. Bethesa: national Center for Biotechnology Information, The ABO Blood Group. 2005;5:1–9.

Chen Z, Yang SH, Xu H, Li JJ. ABO blood group system and the coronary artery disease: An updated systematic review and meta-analysis.Sci Rep; 2016.

Hilde E. Groot Laura E. Villegas Sierra, M Abdullah Said, Erik Lipsic, Jacco C Karper, Pim van der Harst. Genetically determined ABO blood group and its associations with health and disease, arteriosclerosis, thrombosis, and vascular biology. Cleveland Clinic. 2020;40:830–838. Available:https://my.clevelandclinic.org/health/diseases/21053-rh-factor

Arinsburg SA. Pretransfusion testing. In: Shaz BH, Hillyer CD, Gil MR, eds. Transfusion medicine and hemostasis. 3rd ed. Philadelphia, PA: Elsevie.; 2019;21.

Segal GV, Wahed MA. Blood products and blood banking. In: Fowler GC, ed. Pfenninger and Fowler's Procedures for Primary Care. 4th ed. Philadelphia, PA: Elsevier; 2020:chap 234.

Shaz BH, Hilyer CD. Transfusion medicine. In: Goldman L, Schafer AI, eds. Goldman-cecil medicine. 26th ed. Philadelphia, PA: Elsevier. 2020:167.

Westhoff CM, Storry JR, Shaz BH. Human blood group antigens and antibodies. In: Hoffman R, Benz EJ, Silberstein LE, et al, eds. Hematology: Basic principles and practice. 7th ed. Philadelphia, PA: Elsevier. 2018;110.

American college of obstetricians and gynecologists. The Rh factor: How it can affect your pregnancy ; June 2022. Available:(https://www.acog.org/womens-health/faqs/the-rh-factor-how-it-can-affect-your-pregnancy). Accessed 11/10/2022.

American pregnancy association. Rh factor blood type and pregnancy. Available:https://americanpregnancy.org/healthy-pregnancy/pregnancy-complications/rh-factor/. Accessed 11/10/2022.

American red cross. What is the Rh factor? Why is it important?; 2023. Available:(https://www.redcrossblood .org/local-homepage/news/article/what-is-the-rh-factor--why-is-it-important-.html) Accessed 11/10/2022.

March of dimes. RH Disease; 2017. Available:(https://www.marchofdimes.org/complications/rh-disease.aspx). Accessed 11/10/2022.

American college of medical genetics, Newborn screening act sheets and confirmatory algorithms. Available:www.acmg.net/resources/policies/act/condition-analyte-links.htm.