International Journal of Research and Reports in Hematology 2020-11-17T03:13:09+00:00 International Journal of Research and Reports in Hematology Open Journal Systems <p style="text-align: justify;"><strong>International&nbsp;Journal of Research and Reports in Hematology</strong>&nbsp;aims to publish&nbsp;high-quality&nbsp;papers (<a href="/index.php/IJR2H/general-guideline-for-authors">Click here for Types of paper</a>) in all areas of&nbsp;‘Hematology’. This journal facilitates the research and wishes to publish papers as long as they are technically correct, scientifically motivated. The journal also encourages the submission of useful reports of negative results. This is a quality controlled,&nbsp;OPEN&nbsp;peer-reviewed, open access INTERNATIONAL journal.</p> ABH Substances Secretion Status, ABO & Rhesus Blood Groups Typing and P24 Antigen Screening in HIV 1 and 2 Screened Antibody-negative Apparently Healthy Prospective Blood Donors in Calabar, Nigeria 2020-11-02T12:02:00+00:00 Forwah Jacques Ndeh Enosakhare A. Asemota Dorathy Chioma Okpokam Immaculate I. Ekeagba <p><strong>Aim:</strong> To investigate ABH Secretion status, ABO/ Rhesus blood groups and P24 antigen in 400 HIV screened antibody-negative apparently healthy prospective blood donors aged above 20 years recruited within Calabar, Nigeria.</p> <p><strong>Study Design:</strong> experimental, work carried out in the Haematology &amp; Blood&nbsp;&nbsp;&nbsp; Transfusion Unit, Department of Medical Lab Science,University of Calabar Nigeria between December 2009 and December 2010.</p> <p><strong>Methods and Materials: </strong>About 5ml of blood and 3ml of saliva samples were collected by standard procedures from 400 consented selected subjects prior to&nbsp; selection and sera were serologically screened for HIV 1&amp; 2 antibodies using Stat Pak , Determine and Unigold&nbsp; test Kits ,while HIV 1 &amp; 2 antigens were screened&nbsp; using&nbsp;&nbsp; HIV1 and 2 P24 antigens Combi&nbsp; test Kit. Saliva samples analysed for ABH secretor status using BIOTECH Anti-H reagent.&nbsp; ABO/Rhesus blood groups typing were done using blood grouping Anti -sera (A, B, AB, &amp; D) reagents and known red blood cells.</p> <p><strong>Results:</strong> Only 10 samples (02.5 %) reacted positively to the HIV antibody screening panel with two samples (0.2%) out of the 10 samples reacted positive to HIV P24 antigens screening kit. About 11 samples (2.82%) from the tested HIV antibody-negative samples reacted positively to HIV P24 antigens screening kit with 13 positive samples (3.25%).&nbsp; 317 samples (79.25%) were ABH Substance secretors and 83 samples (20.75%) were non-secretors. 4 samples (1%) that were HIV P24 positive were also positive for non-secretor while 9 samples (2.25%) that were positive to P24 antigen screening test were also secretor.</p> <p>The order positive results of P24 antigens screening amongst&nbsp; ABO/Rhesus blood groups&nbsp; positive samples were 2(.5%) for A+ , 4(1%)for B+, 7(1.75%) for O+. A significant statistical difference exists between HIV Antibody and HIV P24 antigen tests&nbsp; (P&lt;0.5). Chi-Square X<sup>2</sup> test shows positive relationship between HIV P24 antigen screening, secretor status, ABO and Rhesus typing results (P&lt;0.5).</p> <p><strong>Conclusion:</strong> ABH Substance secretors were less susceptible to HIV 1 and 2 P24 antigens screened positive test than ABH Substance non-secretors. Blood group O<sup>+</sup>&nbsp;&nbsp;&nbsp; subjects are predisposed to HIV 1 and 2 P 24 antigens screened positive test than A<sup>+</sup> ,B+, AB+, and Rhesus D negative subjects . The risk of infected HIV antibody-negative blood donors has been implicated with a prevalence rate of 3.3%.</p> 2020-11-02T00:00:00+00:00 ##submission.copyrightStatement## Factors Contributing to Anaemia in Children under Five Years in the Ga East Municipality, Ghana 2020-11-17T03:13:09+00:00 Lucy Ofori Stephen Manortey Oscar Vetsi Cynthia Nartey Henry Okorie Ugorji <p>Anaemia is a significant public health issue globally with extreme health consequences. More than two (2) billion individuals have been infected worldwide. A cross-sectional study design was used in this study. The study population included all mothers with children under- five years of age and are residents in the selected communities. A sample size of 282 mothers with children under five years was selected. Multistage sampling technique was used in selecting the sample. The multiple logistic regression models were used to assess the influence of demographic factors on knowledge and prevalence of anaemia. All significant associations and influence were determined at a 0.05 level of significance. The prevalence of anaemia in children was found as 47.9% (95%CI: 42%-54%). Also, family history of anaemia was 49.7% of the respondents. Bivariate analysis showed a significant association among almost all the variables and the anaemia condition in children except for the mother’s age (p=0.486), the number of children (p=0.60) and delivery status (p=0.271). Factors that were statistically significant were mother’s education, mother’s occupation, family type and family income (p&lt;0.001). Again, other factors such as father’s occupation and religious affiliation also had a p-value of &lt;0.01. Child’s birth weight was also significant with p-value=0. 037. It was noted that the high awareness of childhood anaemia among caregivers does not necessarily translate to high knowledge levels. More than half of the participants had poor knowledge on the signs and symptoms, complications and management of childhood anaemia.</p> 2020-11-17T00:00:00+00:00 ##submission.copyrightStatement##