International Journal of Research and Reports in Hematology https://journalijr2h.com/index.php/IJR2H <p style="text-align: justify;"><strong>International&nbsp;Journal of Research and Reports in Hematology</strong>&nbsp;aims to publish&nbsp;high-quality&nbsp;papers (<a href="/index.php/IJR2H/general-guideline-for-authors">Click here for Types of paper</a>) in all areas of&nbsp;‘Hematology’. This journal facilitates the research and wishes to publish papers as long as they are technically correct, scientifically motivated. The journal also encourages the submission of useful reports of negative results. This is a quality controlled,&nbsp;OPEN&nbsp;peer-reviewed, open access INTERNATIONAL journal.</p> International Journal of Research and Reports in Hematology en-US International Journal of Research and Reports in Hematology Assessment of Some Systemic Inflammatory Markers and Haematological Parameters among Pregnant Women in Different Trimesters in Port Harcourt, Nigeria https://journalijr2h.com/index.php/IJR2H/article/view/30138 <p>Pregnancy is a physiological condition that is associated some changes in haematological and immunological parameters. This study evaluated the levels of some systemic inflammatory and haematological parameters in pregnant women in Port Harcourt, Nigeria. A total of 275 pregnant women of age 20 to 70 years and 87 apparently healthy non-pregnant control subjects were involved in this study. Five millilitres (5ml) of blood were collected from the subjects into EDTA bottle for the evaluation of the parameters. ELISA technique was used in the determination of soluble transferrin receptor while Sysmex automation was used for the determination of the other parameters. The mean value of parameters for the study subjects were Hb( 9.05± 1.22g/dl), sTfR( 21.16± 9.11nmol/L), NLR (2.69 ± 0.91), PLR (8.78 ± 2.97), while for control subjects were Hb( 12.19± 0.66g/dl), sTfR( 18.21± 3.77nmol/L), NLR (2.86 ± 0.11), PLR (9.62 ± 2.79). The mean sTfR levels in pregnant women was significantly lower (p=0.001) than in control subjects. The pregnant women also had significantly lower values of Hb (p=0.0001), and PLT (p=0.017). According to trimesters, the levels of sTfR significantly increased with trimester (p=0.002), while that of PLR significantly increased in the second trimester (p=0.006). However, there were no significant differences in the levels of Hb (p=0.185) and NLR (p=0.70) among the trimesters. The results indicate that the pregnant women did not have levels of parameters that may indicate negative outcomes of pregnancy. It is recommended that systemic parameters be monitored among pregnant women in order to help in their medical management.</p> Nyebuchi Jonathan Erens Spiff Ekprikpo Onengiye Davies-Nwalele Lynda K. Giami Evelyn M. Eze ##submission.copyrightStatement## 2021-06-28 2021-06-28 1 7 Hemoglobin and Nutritional Status among the Elderly in Selected Rural Area of Bangladesh https://journalijr2h.com/index.php/IJR2H/article/view/30139 <p><strong>Aims:</strong> To assess the hemoglobin levels and nutritional status of selected elderly people.</p> <p><strong>Study Design:</strong> Cross-sectional observational study.</p> <p><strong>Place and Duration of Study:</strong> Ushayer Hatra village, Mohanpur, Rajshahi, Bangladesh and Institute of Nutrition and Food Science, University of Dhaka, over an one month period.</p> <p><strong>Methodology:</strong> Sixty elderly participants (40 males, 20 females; age range 60-95 years) were included, all being non-hospitalized, non-smoker, non-alcoholic and no one having any history of recent major blood loss. Hb analysis was done by Cyanmethemoglobin method. Anthropometric measurements (height, weight and mid upper arm circumference) were taken following standard measurement guidelines of the World Health Organization. Socio-economic data were collected using a pre-tested questionnaire.</p> <p><strong>Results:</strong> The mean (±SD) Hb content was higher in males than females (11.87 (±1.50) g/dL in males and 10.16 (±1.04) g/dL in females) and the difference was highly statistically significant (<em>P</em> &lt; .0005). Low Hb levels (&lt;13 g/dL in males and &lt;12 g/dL in females) in 67.5% male and 95.0% female participants were observed. The mean BMI of males and females were 21.76 kg/m<sup>2 </sup>and 22.58 kg/m<sup>2</sup> respectively. Fifty percent female and 57.5% male participants were in normal body weight (BMI=18.5-24.9 kg/m<sup>2</sup>). The Mean value of MUAC were 27.13 cm in males and 25.14 cm in females. Based on MUAC, 90.0% male and 75.0% female participants had normal nutritional status (MUAC ≥ 23.5 cm in males and ≥ 22 cm in females). The association between BMI and MUAC categories of the participants were found to be statistically significant in both groups (<em>P</em> =.049 and .001 in male and female groups respectively).&nbsp;</p> <p><strong>Conclusion:</strong> Most of the study participants had low hemoglobin levels but normal nutritional status. However, further studies with considerable sample size are required to determine the prevalence of&nbsp; anemia and malnutrition among the elderly people of&nbsp; Bangladesh.</p> Tanveer Akik Ibne Alam Md Sujan Hossen Iftekhar Hasan Md. Akhtaruzzaman Md. Saidul Arefin ##submission.copyrightStatement## 2021-08-07 2021-08-07 8 16 Effect of Hydroethanolic Extract of Fleurya Aestuans on Haematological Parameters and Oxidative Indices of Phenylhydrazin Induced Toxicity https://journalijr2h.com/index.php/IJR2H/article/view/30140 <p><em>Fleurya aestuans</em> popularly called West Indian Wood Nettle is known for its therapeutic potential as it has been long used by herbalists in managing many diseases. The haematinic efficacy of the leaves of this plant was examined in this study.&nbsp; A total of 43 rats were procured, 13 rats were used for lethal dose (LD<sub>50</sub>) studies while the remaining 30 rats were grouped into six groups of five rats each and allowed to acclimatize for two weeks.&nbsp; Groups 1 served as control and were administered 2ml/kg of the extract vehicle, group 2 served as negative control, groups 3 and 4 served as test group and were administered with 50 mg per body weight of <em>Fleurya aestuans</em> leaf extract and 200 mg per body weight of same extract, while group 5 and 6 were administered with 0.23 ml per body weight of bioferon and 100 mg per body weight of Kaempferol respectively. Phenyl hydrazine was used to induce the anaemia in all the groups; the extract was prepared and administered orally using oral gavage. Blood samples were collected through ocular puncture after 14 days and analysed for haematological parameters using standard manual methods. Results showed that the extract significant (P &lt; 0.05) enhanced the low levels RBC counts, Hb concentration, PCV, SOD, CAT and GSH levels but reduced the abnormally elevated levels of MCV, MCHC, MDA, WBC and Platelets counts. The oral administration of <em>Fleurya aestuans</em> leaf extract could be useful both in boosting blood parameters and combating diseases irrespective of the anaemia and leukocytosis caused by phenylhydrazine therapy.</p> C. N. Charles F. S. Amah-Tariah D. V. Dapper ##submission.copyrightStatement## 2021-08-13 2021-08-13 17 27 Impact of (ELIOZU) Dumpsite Leachates on Some Haematological Parameters in Wistar Rats https://journalijr2h.com/index.php/IJR2H/article/view/30141 <p>Leachates contain deleterious constituents that may cause contamination of ground and surface water leading to serious risks to the ecosystem and human health. The exposure of the environment to dumpsite leachate may occur in different ways, such as uncontrolled overflow, rainfall and infiltration. This study therefore, attempts to determine the possible effects of (Eliozu) dumpsite leachates on some haematological parameters in Wistar rats. 25 Wistar rats weighing between 180g and 250g were divided into five groups of 5 animals each. Groups are as follows: Group 1: received 1ml of commercial bottle water, Group 2: received near-by borehole water, Group 3: received 10% of leachate concentrations, Groups 4 and 5: received 50% and 100% of leachate concentrations every 24 hours for 90 consecutive days. At the end of the gavaging of the leachates, blood samples were collected for heamatological parameters analysis using automated method. Results obtained shows a significant (p&lt;0.001) reduction in some hematological parameters compared with control. Paradoxically, the mean corpuscular volume (MCV), red blood cell distribution width-standard deviation and red blood cell distribution width-coefficient of variation show significant increase (p&lt;0.001) compared with the control. There were also significant decreases in weights of the experimental animals while compared with the control group. Eliozu dumpsite leachates demonstrated some toxicological potentials on Red Blood Cells (RBCs) and RBC indices; White Blood Cells (WBCs) and WBC Differentials in Wistar rats. We recommend further studies in this regard.</p> I. I. Weleh I. E. Weleh I. K. Green ##submission.copyrightStatement## 2021-08-19 2021-08-19 28 36